Systema excitans reticulare ascendens

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Truncus encephali cum partes systematis excitantis reticularis ascendentis.

Systema excitans reticulare ascendens est collectio nucleorum in trunco cerebri vertebratorum situata. Systema hoc simul est ipsa pars formationis reticularis, quae fibras nervales (ascendentes) in corticem cerebri mittit. Munera eius est statum vigilantem et numerum circadianum multiplicium fibrarum nervorum in cortices cerebri ambos distribuentium ope sustentare[1]. Hoc in modum quaequae undarum EEG generatae sunt[2].

Nuclei systematis excitantis reticularis ascendentis intra formatione reticulari et etiam thalamo cum systematibus neurotransmissorum acetylcholini, dopamini, acidi glutamici, histamini, noradrenalini, serotonini inveniuntur.

Damnum systematis excitantis reticularis ascendentis, ut in apoplexia cerebri, perturbationes graves perficiat[3], at sanitas recuperata nonnumquam observata est[4].

De systematibus neurotransmissorum[recensere | fontem recensere]

Quaedam systemata neurotransmissorum systema excitans reticulare ascendens formant. Systema neurotransmissoris hic ad multitudinem neuronorum aequalium eodem neurotransmissore ex terminalibus synapticis liberato spectat. Verbi gratia systemate dopaminergico cellulae nervales cum synapticis dopaminergicis neurotransmissorem dopaminum liberant, incitantque postsynaptice receptoria dopaminergica.

Partes principales systematis excitantis reticularis ascendentis
Systema Neuro
transmissor
Correspondentes nuclei
animum excitationem mediantes
Fontes
dopaminergicum dopaminum [5]
noradrenergicum noradrenalinum
serotonergicum serotoninum
histaminergicum histaminum
cholinergicum acetylcholinum
glutamatergicum glutamatum
Nuclei thalami

Systema dopaminergicum[recensere | fontem recensere]

In mesencephalo imprimis duo nuclei, cuius synapses neurotransmissorem dopaminum liberant, inveniuntur: substantia nigra, pars compacta (A9), ac area tegmentalis ventralis (A10).

Notae[recensere | fontem recensere]

  1. Schwartz J. R., Roth T. (2008). "Neurophysiology of sleep and wakefulness: basic science and clinical implications". Curr Neuropharmacol 6 (4): 367-78 
  2. Brown R. E., McKenna J. T. (2015). "Turning a Negative into a Positive: Ascending GABAergic Control of Cortical Activation and Arousal". Front Neurol 6: 135 
  3. Boukrina O., Barrett A. M.. (2017). "Disruption of the ascending arousal system and cortical attention networks in post-stroke delirium and spatial neglect". Neurosci Biobehav Rev 83: 1-10 
  4. Jang S. H., Kim S. H., Lim H. W., Yeo S. S. (2015). "Recovery of injured lower portion of the ascending reticular activating system in a patient with traumatic brain injury". Am J Phys Med Rehabil 94 (3): 250-3 
  5. Iwańczuk W., Guźniczak P. (2015). "Neurophysiological foundations of sleep, arousal, awareness and consciousness phenomena. Part 1". Anaesthesiology intensive therapy 47 (2): 162-7 

Nexus interni