Area tegmentalis ventralis

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Area tegmentalis ventralis
Tegementum
Area tegmentalis in mesencephalo locata est.
Itinera dopamini.
Area tegmentalis ventralis (VTA) cum substantia nigra

Area tegmentalis ventralis (TA: 14.1.06.007) (abbreviatura internationalis VTA) est grex neuronorum A10 et initium itineris mesocorticolimbici ad corticem praefrontalem. Neurotransmissor est dopaminum. Parti systematis remunerationis areae tegmentali ventrali munera cognitionis, motivationis, orgasmi sunt[1].

Anatomia[recensere | fontem recensere]

Area tegmentalis ventralis in gregres anteriorem et posteriorem dividitur. Insunt:

  • area parafasciculi retroflexi
  • area parabrachialis
  • nucleus parainterfascicularis
  • nucleus paranigralis
  • cauda tegmentalis ventralis

Itinera afferentia[recensere | fontem recensere]

Receptoria et GABA (GABAA) et adrenergica α1 (α1-AR) responsa VTA movent[2].

Itinera efferentia[recensere | fontem recensere]

Axones in corticem praefrontalem[3], gyrum cinguli, hippocampum, nucleum accumbentem, bulbum olfactorium, amygdalam prodeunt.

Notae[recensere | fontem recensere]

  1. Holly E. N., Miczek K. A. (2016). "Ventral tegmental area dopamine revisited: effects of acute and repeated stress". Psychopharmacology (Berl) 233 (2): 163-86 
  2. Velásquez-Martínez M. C., Vázquez-Torres R., Rojas L. V., Sanabria P., Jiménez-Rivera C. A. (2015). "Alpha-1 adrenoreceptors modulate GABA release onto ventral tegmental area dopamine neurons". Neuropharmacology 88: 110-21 
  3. Puig M. V., Antzoulatos E. G., Miller E. K. (2014). "Prefrontal dopamine in associative learning and memory". Neuroscience 282: 217-29 

Nexus interni