Nucleus centromedianus

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Nucleus centromedianus expressis verbis in centro thalami locatus est.

Nucleus centromedianus (TA: 14.1.08.618, abbreviatura CM) pars (grex posterior/caudalis) utriusque lateris nucleorum intralaminares thalami est. In nonnullis cursis morborum, ut in morbo Parkinson vel in paralysi supranucleari progressiva, hic nucleus quoque damnum patiatur[1].

Nucleus centromedianus, ut nucleus centrolateralis, cum corticibus associationis sensori-motorici connectus est. Neurotransmissor eius acidum glutamicum (GLU) est.

Effectus[recensere | fontem recensere]

Nucleus centromedianus sub morbis diversis[recensere | fontem recensere]

In nonnullis epilepsiis tractandis stimulatio nuclei centromediani utile possit[2], etiam computatri ope[3]. Stimulatio nuclei sane interdum aggressionem perficere potest[4].

Notae[recensere | fontem recensere]

  1. Henderson J. M., Carpenter K., Cartwright H., Halliday G. M. (2000). "Loss of thalamic intralaminar nuclei in progressive supranuclear palsy and Parkinson's disease: clinical and therapeutic implications". Brain 123 (Pt 7): 1410-21 
  2. Kim S. H., Lim S. C., Yang D. W., Cho J. H., Son B. C., Kim J., Hong S. B., Shon Y. M. (2017). "Thalamo-cortical network underlying deep brain stimulation of centromedian thalamic nuclei in intractable epilepsy: a multimodal imaging analysis". Neuropsychiatr Dis Treat 13: 2607-2619 
  3. Gummadavelli A., Zaveri H. P., Spencer D. D., Gerrard J. L. (2018). "Expanding Brain-Computer Interfaces for Controlling Epilepsy Networks: Novel Thalamic Responsive Neurostimulation in Refractory Epilepsy". Front Neurosci 12: 474 
  4. Yan H., Boutet A., Mithani K., Germann J., Elias G. J. B., Yau I., Go C., Kalia S. K. et al. (Nov 2019). "Aggressiveness after centromedian nucleus stimulation engages prefrontal thalamocortical circuitry". Brain stimulation: S1935-861X 

Nexus interni

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