Nucleus supraopticus
| Nucleus supraopticus | ||
|---|---|---|
| Cognitores | ||
| TA: | A14.1.08.912 | |
| Anatomia | ||
 | ||
| Sectione frontale (coronali) situs nuclei supraopticus (SON) immediate supra tractum opticum (OT) est. 3V = ventriculus tertius | ||
Nucleus supraopticus est nucleus hypothalamicus ex tribus milibus cellularum magnocellularium compositus. Cellulae haec hormonta et vasopressinum et oxytocinum in sanguinem liberant[1]. Locatus est nucleus supraopticus in regione anteriori, immediate supra chiasma opticum.
Anatomia microscopica[recensere | fontem recensere]
Nucleus supraopticus haud magnus apparet, ei tantum circiter tria milia neuronorum insunt. Zona perinuclearis nucleo ipso vicina est.
Circuitus[recensere | fontem recensere]
Axona nervi supraoptici in partem posteriorem hypophysis ducunt[2]:
- Nucleus supraopticus → pars posterior glandulae pituitariae
Videtur ut axona nervi supraoptici etiam in organi suprafornicalis neurona terminent, quae axona in nucleum paraventricularem mittunt[3]:
- Nucleus supraopticus → organum suprafornicale → nucleus paraventricularis
Physiologia[recensere | fontem recensere]
Cellulae haec hormon vasopressinum secernunt, quod, trans sanguinem missum, in renibus reabsorptionem natrii Na+ auget. Generant nuclei cellulae etiam hormon oxytocinum[4].
Si pressio sanguinis augeat, zona periventricularis inhibitionis neuronorum vasopressini necesse sit[5].
Notae[recensere | fontem recensere]
- ↑ Hirasawa M., Mouginot D., et al. (Mai 2003). "Vasopressin differentially modulates non-NMDA receptors in vasopressin and oxytocin neurons in the supraoptic nucleus". The journal of neuroscience 23 (10): 4270-7
- ↑ Kombian S.B., Hirasawa M., et al. (2002). "Modulation of synaptic transmission by oxytocin and vasopressin in the supraoptic nucleus". Progress in brain research (139): 235-46
- ↑ Kawano H. (Apr 2017). "Synaptic contact between median preoptic neurons and subfornical organ neurons projecting to the paraventricular hypothalamic nucleus". Experimental brain research 235 (4): 1053-62
- ↑ Takayanagi Y., Yoshida M., et al. (Feb 2017). "Synaptic contact between median preoptic neurons and subfornical organ neurons projecting to the paraventricular hypothalamic nucleus". Biological psychiatry 81 (3): 243-51
- ↑ Grindstaff R. R., Cunningham J. T. (Mar 2001). "Lesion of the perinuclear zone attenuates cardiac sensitivity of vasopressinergic supraoptic neurons". American journal of physiology 280 (3): R630-8