Fontem paginae Gravedo inspicere

{{videdis|Gravedo (discretiva)}}
[[Fasciculus:Rhinovirus.PNG|thumb|[[Rhinovirus]], causa plurimarum gravedinum]]
'''Gravedo,''' vel hodiernis vocibus [[medicina|medicis]] '''rhinitis acuta catarrhalis''' et '''nasopharyngitis''' et '''acutus rhinopharyngitis viralis''' et '''acuta coryza,''' est [[virus biologicum|viralis]] superioris [[systema respiratorium|systematis respiratorii]] [[morbus]], praecipue a [[rhinovirus|rhinoviris]] et [[coronavirus|coronaviris]] effectus.<ref>{{DorlandsDict|nine/000951572|common cold}}</ref> Ea est communissimus inter [[homo|homines]] [[morbus]].
 
Communes gravedinis notae sunt [[pharyngitis]], [[rhinitis]], [[congestio nasalis]], [[sternumentum]], et [[tussis]], aliquando cum [[coniunctivitis|comiunctivitide]], [[myalgia]], [[fatigatio]]ne, [[lassitudo|lassitudine]], [[capitis dolor|capitis dolore]], [[debilitas musculorum|debilitate musculorum]], impotentia [[tremor (symptoma)|tremoris]], et [[anorexia]]. Extremae per gravedinem [[febris]] [[fatigatio]]que sunt rarae, licet usitatiores per [[influenza]]m, aliam superioris [[systema respiratorium|systematis respiratorii]] [[infectio]]nem, cuius notae notis gravedinis simillimae sunt (Eccles 2005), quamquam severiores (Nordenberg 1999).

Morbi indicia solent post circa [[hebdomas|septem dies]] non comparere, sed usque ad quattuordecim durare possunt, infantibus et parvulis graviora quam adultis. Quamquam morbus lenis et definitus esse solet, gravedine laborantes saepe auxilium medicorum confirmatorum<!--certified = professional?--> petunt, [[medicamentum libere coemptum|medicamentis libere coemptis]]<!--over-the-counter--> utuntur, et interdum scholam laboremve amittunt. Gravedinis societati per annum pretium magnopere remediorum sumptu et "productivitatis" amissae horis stat.
 
Non sunt [[antiviral]]ia ad contagionem curandam medicamenta rite approbata; omnia gravedinis medicamenta sunt exempla [[curatio pallians|curationis palliantis]], quae morbi notas solum extenuat. Etsi nonnulla remedia "alternativa," sicut [[megapotio vitamini C]], ''[[Echinacea (planta)|echinacea]],'' et [[zincum]] proposita sunt, non sunt eorum efficacitatis firma argumenta (American Lung Association 2005); ergo nullum ab [[Administratio Ciborum et Medicamentorum|Administratione Ciborum et Medicamentorum]] ([[Anglice]] ''Food and Drug Administration'') vel [[Europaea Medicamentorum Administratio]]ne ([[Anglice]] ''European Medicines Agency'') approbatum est. Ad contagionem impediendam, [[lavatio manuum|lavatio manuum]] monstrata est efficax.<!--as this minimizes person-to-person transmission of the virus.-->

== Morbi notae ==
[[Fasciculus:Hapci-fr.gif|200px|thumb|Sternumentum saepe initium gravedinis significat.]]
Post contagionem, replicatio viralis post [[octo]] ad [[duodecim]] [[hora]]s incipit (Gwaltney & Hayden 2006). Morbi notae mox evenire possunt, et ferme post [[duo]] ad [[quinque]] dies post contagionem, quamquam raro solum ante [[decem]] horas post contagionem (Hamilton n.d.). Primum gravedinis signum saepe est [[pharyngitis]]. Aliae notae communes sunt [[rhinorrhea]], [[congestio nasalis]], [[sternumentum]], et [[tussis]]. Haec indicia aliquando cum [[myalgia]], [[fatigatio]]ne, [[lassitudo|lassitudine]], [[capitis dolor]], [[debilitas musculorum|debilitate musculorum]], vel [[anorexia]] eveniunt (Common Cold Centre 2006); ea ferme sua sponte solvuntur post septem ad decem dies, sed nonnulla in viginti-unum dies persistunt (Heikkinen et al. 2003). [[Infantulus|Infantulis]], [[puer]]ulis, et quibus [[tabacum|tabaco]] utuntur, morbi notae possunt esse severiores, et possunt includere [[febris|febrim]] et [[urticaria]]m (American College of Allergy, Asthma & Immunology n.d.; American Lung Association 2005; Canadian Lung Association 2006; Canadian Pediatric Society 2005a; National Institute of Allergy and Infectious Diseases 2006; Nordenberg 1999).
 
== Causa et mollitia ==
Gravedo saepissime efficitur ab contagione [[unus|unius]] ex plus quam [[centum]] [[serovar]]ibus [[rhinovirus|rhinoviri]], generis [[picornavirus|picornaviri]]. Alia vira gravedines moventia sunt [[coronavirus]], [[humana parainfluenzae vira]], [[respiratorium virus syncytiale humanum]], [[adenovirus|adenovira]], [[enterovirus|enterovira]], et [[metapneumovirus]] (Clinical Knowledge Summaries Service 2007; The Merck Manual Online 2005). Quia sunt multa virorum genera distincta, quae praeterea perpetuo mutantur, nullo modo fieri potest gravedinis immunitatem consequi.
[[Fasciculus:Blowing snow in Norway.jpg|thumb|left|Exponi in caelo frigido non monstratum est probabilitatem gravidinis "captae" augere.]]

Insomniae cum gravedine consociatae sunt. Tripliciter probabilius est ut rhinoviro expositi infectionem contrahant qui minus septenis horis in [[nox|nocte]] dormiunt quam qui magis octonis (Cohen et al. 2009).

[[Fabula]] vetus, iam communis, gravedinem contrahi docet cum quis diu caelo frigido exponitur, velut [[pluvia|pluviae]] aut [[gelu|gelui]] [[hiems|hiberno]] (Zuger 2003). Quamquam gravedines sunt tempestivae (plures per hiemem eveniunt), investigationes hactenus non probaverunt exponi in caelo frigido, etiam refrigerari, augere mollitiam infectionis; quod in se habet variationem tempestivam potius ostendere mutationem morum, sicut tempus intus auctum iuxta alios (Douglas, Couch, & Lindgren 1967; Douglas, Lindgren, & Couch 1968; Dowling et al. 1958; Eccles 2002; National Institute of Allergy and Infectious Diseases 2006).
 
Quod attinet ad causam notarum gravedinis similium, investigatores in Common Cold Centre [[Universitas Cardiff|Universitatis Cardiff]] (Common Cold Centre 2006) studium fecerunt ut temparetur hypothesis acute refrigerare [[pes|pedes]] initium notarum gravedinis efficere (Johnson 2005; Smith 2005).<!-- Investigatio measured the subjects' self-reported cold symptoms, and belief they had a cold, but not whether an actual respiratory infection developed.--> Repperit significanter{{dubsig}} maior numerus hominum refrigeratorum notas gravedinis evolvit quattuor vel quinque dies post refrigerationem. Concludit initium notarum gravedinis ab acuta [[pes|pedum]] refrigeratione effici potest. <!-- Some possible explanations were suggested for the symptoms, such as placebo, or constriction of blood vessels of the nasal passages which might lead to reduced immunity, however "further studies are needed to determine the relationship of symptom generation to any respiratory infection."
 
Another possibility which remains to be explored involves the role that proteins of the complement system play in the prevention of a sustained infection. Decreased temperature may result in a drop in tissue permeability and, as a result, may lead to reduced plasma leakage. Among the many proteins suspended in plasma are complement proteins (exempli gratia, C3) which serve to disable, destroy, or tag for destruction foreign particulate (in this case viral [[capsid]]s). Thus, sustained exposure to cold may inhibit the effectiveness of the complement system and allow the virus a better chance of establishing a state of infection. -->
 
ICAM-1, receptor ad quem se rhinovirus ligat ut [[cellula]]s inficiat, numero et receptivitate{{dubsig}} multis stimulis respondens, [[pulvis|pulvere]] [[pollen|pollineque]] non exclusis, augetur. An [[caelum]] frigidum, cum variis [[humiditas|humiditatis]] gradibus, possit esse stimulus similis, est investigandum.

== Pathophysiologia ==
[[Fasciculus:Illu conducting passages.svg|thumb|Gravedo est morbus [[superior tractus respiratorius|superioris tractus respiratorii]] (tabula [[Anglice]] signata).]]
Virus gravedinis homines duobus modis inter se communicant: in primis contagione [[saliva|salivae]] vel secretionum nasalium hominis infecti, vel rectá formá [[aerosolium|aerosolii]]{{dubsig}} a tussibus sternutamentisque generata, vel ex superficiebus contaminatis (Kolata 2007). Morbi notae non requiruntur a virali effusione vel transmissione; aliqua subiecta asymptomatica vira in culturis nasalibus exhibent (Department of Health, Government of South Australia 2005).
 
Usitatus viri aditus est [[nasus]], sed possunt esse [[oculus|oculi]], per derivationem in [[nasopharynx|nasophyringem]] et tum per [[ductus nasilacrimalis|ductum nasilacrimalem]], unde ad intimum nasum et regionem [[adenoidum|adenoidorum]]{{dubsig}} refertur. Virus tunc se adfigit ad receptorem [[ICAM-1]], qui est in superficie [[cellula]]rum membranae nasopharyngis, ad quam receptor in superficiali viri aditu advenit. Multi viri receptores adsunt in cellulis adenoidi. Postquam se ad receptorem adfixit, virus vehitur in cellulam, ubi infectio statim initium capit (Gwaltney & Hayden 2007). <!--The common cold is self-limiting, and the host's [[immune system]] effectively deals with the infection. Within a few days, the body's [[humoral]] immune response begins producing specific [[antibodies]] that can prevent the virus from infecting cells. Additionally, as part of the cell-mediated immune response, [[leukocytes]] destroy the virus through [[phagocytosis]] and destroy infected cells to prevent further viral replication.--> In singulis sanis et immunocompetentibus, gravedo [[septem]] [[dies|diebus]] cessare solet (Gwaltney & Hayden 2006).

== Morbi complexiones ==
Gravedo [[infectio opportunistica|opportunisticas]] [[coinfectio]]nes vel [[superinfectio]]nes sicut [[bronchitis acutus|bronchitidem acutum]], [[bronchiolitis|bronchiolitidem]], [[croup]],{{dubsig}} [[pneumonia]]m, [[sinusitis|sinusitidem]], [[otitis media|otitidem mediam]], et [[fauces strepitantes]] generare potest.<!--strep throat--> Homines quibus sunt chronici morbi [[pulmo|nis]], sicut [[asthma]] et [[morbus chronicus obstructionis pulmonum|COPD]] (Anglice), sunt praecipue propensi. Gravedines acutas [[asthma]]e, [[emphysema]]e, et [[bronchitis chronicus|bronchitidis chronici]] exacerbationes efficere possunt (Clinical Knowledge Summaries Service 2007; Gwaltney & Hayden 2006; The Merck Manual Online 2005).

== Morbi tractatio ==
Gravedo plerumque solvitur ultro per septem ad decem dies, sed aliae notae possunt persistere ad viginti unos dies (Heikkinen et al. 2003). Absunt medicamenta vel remedia herbalia quae temporis spatium morbi certo praecidere possunt. Curatio saepe datur formá [[medicamentum|medicamenti]] doloris et aliarum notarum, ut aeger adlevetur et implicationes nocentesque [[sequelae]] circumscribantur.
 
===Commendationes=== <!--
[[National Institute of Allergy and Infectious Diseases]] suggests getting plenty of rest, drinking fluids to maintain hydratio, [[gargarizatio]] cum calida aqua salsa, using cough drops, throat sprays, or [[medicamentum libere coemptum]] pain or cold medicines (National Institute of Allergy and Infectious Diseases 2006). Saline nasal drops may help alleviate congestion (PDRHealth n.d.). -->
Curationes quae notas adlevant includunt: [[analgesica]]s, [[decongestans|decongestantes]], et [[res quae tusses supprimunt]], [[antihistamina]]s generationis primae sicut [[brompheniramina]]m, [[chlorpheniramina]]m, [[diphenhydramina]]m, et [[clemastina]]m<!-- (which reduce mucus gland secretion and thus combat blocked/runny noses but also may make the user drowsy). Second-generation antihistamines do not have a useful effect on colds (Canadian Pediatric Society 2005b).-->
 
==== Antibiotica ====
[[Antibiotica]], quia sola [[bacteria]] oppugnant, effectum salutarem contra gravedinem non habent.

==== Antivirales ====
Non sunt gravedinis [[medicamentum antivirale|medicamenta antiviralia]] rite approbata. 
 
==== Medicinae gravedinis ====
Sunt variae [[medicinae pro tussi]]bus quae postulantur notas levare. Hae medicinae [[mucolyticae|mucolyticas]]{{dubsig}}, [[expectorantes]]{{dubsig}}, [[antitussivi|antitussivos]]{{dubsig}}, [[antihistaminum|antihistamina]]{{dubsig}}, et [[anticongestantes]]{{dubsig}} includunt. Non autem commendantur pro usu puerulorum (UpToDate Inc. n.d.).

=== Curationes "alternae" ===
[[Fasciculus:EchinaceaPurpureaMaxima1a.UME.JPG|thumb|Tinctura ''[[Echinacea purpurea|Echinaceae]]'' a multis habetur "alternativa" gravedinis curatio.]]
Multae curationes "alternae" gravedinem curare adhibentur; nulla autem firmis indiciis [[Scientia (ratio)|scientificis]] sustinetur (American Lung Association 2005). Etenim aliae curationes "alternae," sicut [[echinacea (planta)|echinacea]] (Bergner 1997; Turner et al. 2005), hactenus videntur celeritatem infectionis vel temporis spatium severitatemve notarum gravedinis non mutare (National Center for Complementary and Alternative Medicine 2005; ''New England Journal of Medicine'' 2005).
 
Aliae curationes "alternae", quae similiter firmis indiciis scientificis carent, [[calendula]] (Jimenez-Medina et al. 2006), [[zingiber]] (Jakes 2007), [[Allium sativum|allium]] (Hamel & Chiltoskey 1975), et supplementa [[vitaminum C|vitamini C]] (Cathcart 1996) sunt.

== Prohibitio ==
Optimus gravedinem prohibendi modus est manus penitus ordinatimque lavare, et [[oculus|oculos]], [[nasus|nasum]], [[facies|faciem]] tactas vitare. [[Sapo]]nes antibacteriales virus gravedinis non adficiunt; quod particulas viri removet est mechanica manuum lautorum sapone actio (Public Health Agency Canada 2008). <!-- Anno 2002, [[Centers for Disease Control|Centers for Disease Control and Prevention]] recommended alcohol-based hand gels as an effective method for reducing infectious viruses on the hands of health care workers (Boyce & Pittet 2002). As with hand washing with soap and water, alcohol gels provide no residual protection from re-infection. --> Gravedo a multis viris variis efficitur, quae frequentissime per reproductionem mutantes stirpes virales quae perpetuo mutantur gignunt; prospera ergo [[immunizatio]] est non verisimilis.
 
== Epidemiologia ==
Infectiones in superiore tractu respiratorio sunt communissimi morbi contagiosi adultorum et adulescentium, qui duas ad [[quattuor]] infectiones respiratorias per annum patiuntur (Garibaldi 1985). Pueruli sex ad decem gravedines per annum patiuntur; pueri in scholis ad decem per annum (National Institute of Allergy and Infectious Diseases 2006; Simasek & Blandino 2007).
 
In [[Hemisphaerium Septentrionale|Hemisphaerio Septentrionali]], casus gravedinum sunt [[autumnus|autumnali]] [[hiems|hiemalique]] tempore maiores, et plurimae infectiones inter Septembrem Aprilemque incidunt. Haec ratio tempestiva fortasse incipium anni scholastici ostendit, vel maius tempus cum homines intus iuxta alios sint, casu transmissionis viri augenti (National Institute of Allergy and Infectious Diseases 2006).

== Etymologia et historia ==
Gravedinis in multis [[lingua|linguis]] verbum similitudini notarum gravedinis notarumque actus [[caelum|caelo]] [[frigor|frigido]] exponendi respondet. Sic omnes [[linguae Romanicae]]:
* [[Dacoromanice]]: ''rece'' 'frigidum', ''răceală'' 'gravedo'
* [[Francogallice]]: ''froid'' 'frigidum', ''refroidissement'' 'gravedo'
* [[Hispanice]]: ''frio'' 'frigidum', ''resfriado'' ' gravedo'
* [[Lingua Italica|Italice]]: ''freddo'' 'frigidum', ''raffreddarsi'' 'frigore tangi', ''raffreddore'' 'gravedo'
* [[Lusitanice]]: ''frio'' 'frigidum', ''resfriado, resfriamento'' 'gravedo'

Sic etiam in [[lingua Graeca]]: ''κρύο [kryo]'' 'frigidum', ''(το) κρυολόγημα [(to) kryológēma]'' 'gravedo'; in [[lingua Theodisca]]: ''kühl'' 'frigidum', ''abkühlen'' 'frigore tangi'; in [[lingua Croatica]] (una ex [[linguae Slavicae|linguis Slavicis]]): ''hladno'' 'frigidum', ''prehlada'' 'gravedo', in [[lingua Hungarica]] ([[Linguae Finno-Ugricae|Finno-Ugrica]]): ''hűvös'' seu ''fagy'' seu ''hideg'' 'frigidum', ''hűl'' 'frigore tangi', ''fázik'' 'frigerare', ''meghűlés'' seu ''megfázás'' 'frigeratio'.

Sic etiam in [[lingua Havaiana]], una ex [[linguae Polynesiae|linguis Polynesiis]]: ''anu'' 'frigidum', ''anu'' 'gravedo, gravedine laborare'.
[[Fasciculus:Definition of a Cold by Benjamin Franklin Page 1.jpg|thumb|''Definition of a Cold'' ('Definitio gravedinis'): adnotationes a [[Beniaminus Franklin|Beniamino Franklin]] scriptae ut commentarium de gravedine designaret.]]

[[Lingua Anglica|Anglice]], nomen ''common cold'' [[saeculum 15|saeculo quinto decimo]] similiter evolvit.<ref>[http://www.etymonline.com/index.php?term=cold ''Online Etymology Dictionary'' apud www.etymonline.com] "Cold," ''Online Etymology Dictionary,'' inventum 12 Ianuarii 2008.</ref> Norman Moore in sua historia studii medicinae scripsit [[Iacobus I (rex Angliae)|Iacobum I]] Angliae regem gravedinibus continenter laborasse, quae a [[Polypus (medicina)|polypis]], incommodis [[sinus|sinibus]], vel [[autotoxaemia|autotoxaemiá]] effici tunc habitae sunt (Wylie 1927:81–87). [[Saeculum 18|Saeculo duodeviginti]], [[Beniaminus Franklin]] gravedinis causas prohibitionemque animadvertit; post nonnullos investigationis annos, concludit: "Homines saepe inter se gravedinem communicant cum in parvis [[conclave|conclavibus]], [[raeda|raedis]], etc. spisse includantur, et prope conlocati conloquantur ut spiritu inter se hauriant." Quamquam vira non iam reperta erant, Franklin opinatus est gravedinem inter homines per [[aer]]em communicari. Ut homines gravedinem prohibeant, commendavit exercitationem, lavationem, et in [[cibus|cibo]] [[potio]]neque continentia (American Treasures of the Library of Congress n.d.). Haec theoria de communicatione gravedinis post centum quinquaginta annos confirmata est (Andrewes et al. 1951).

In [[Britanniarum Regnum|Britanniarum Regno]], [[Unitas Gravedinis]] ([[Anglice]] ''Common Cold Unit'') anno [[1946]] abs [[Consilium Investigationis Medicae]] ([[Anglice]] ''Medical Research Council'') constituta est. Haec unitas cum voluntariis laboravit, quos variis viris infecit (Schneider 2004). [[Rhinovirus]] ibi repertum est (Tyrrell 1988). Decennio 195 exeunti, investigatores unum ex his rhinoviris in [[cultura carnis]] ([[Anglice]]: ''tissue culture'') aluerunt, quia in fertilibus [[pullus|pullorum]] [[ovum|ovis]] non crevit—ratio pro multis aliis viris adhibita. [[Decennium 198|Decennio 198]], haec unitas monstravit curationem cum [[interferon]] per incubationem rhinoviro contagionis morbum aliquantum prohibere (Tyrrell 1987), sed efficax curatio evolvi non potuit. Unitas clausa est anno [[1989]], duos annos postquam investigaverat proprietates [[pastilla]]rum [[gluconas zinci|gluconatis zinci]] ad gravedinum rhinovirorum prohibendam curandamque—solum prosperum medicamentum ab unitate factum (Al-Nakib 1987).

In [[CFA|Civitatibus Foederatis Americae]], gravedo facit ut 75 ad 100 milliones [[homo|hominum]] [[medicus|medicos]] per annum visant, sumptu $7.7 billionarum{{dubsig}} aestimatarum. Americani $2.9 billionas{{dubsig}} in [[medicamentum libere coemptum|medicamenta libere coempta]] insumunt, et alias $400 millionas{{dubsig}} in medicamenta praescripta pro levatione morbi notarum (Fendrick & al. 2003; Garibaldi 1985). Plus quam tertia pars eorum qui medicum consuluerunt [[praescriptio]]nem antibioticam acceperunt—quod adficit resistentiam{{dubsig}} antibioticam propter nimium talium medicamentorum usum (Fendrick & al. 2003). Fortasse 22 ad 189 milliona{{dubsig}} [[dies|dierum]] [[schola]]e ob gravedinem amittuntur. Parentes ergo circa 126 milliona dierum laboris amittuntur ut ei domi maneant liberosque curent. Quia homines ipsi a gravedinibus tacti circa 150 milliona dierum laboris amittunt, totus gravedinum effectus [[oeconomia|oeconomicus]] circa $20 billiona per annum excedit (Fendrick & al. 2003; Garibaldi 1985; National Institute of Allergy and Infectious Diseases 2006).

== Investigationes scientificae ==
Societas [[Biota Holdings]] medicamentum evolvit, nunc appellatum BTA798, quod rhinovirus petit; quod medicamentum examinationes clinicas "Phase IIa" nuper complevit.<ref name="mailonline">{{cite web| url = http://www.dailymail.co.uk/health/article-1043719/The-new-pill-signal-death-common-cold.html | title =  The new pill that could signal the death of the common cold| publisher = ''Daily Mail'' | month = August| year = 2008| accessdate = 19 August 2009}}</ref><ref name="biotarelease">{{cite web| url = http://www.biota.com.au/uploaded/154/1021521_38hrvphaseiiastudyachieve.pdf | title =  Biota Press Release | month = June| year = 2009| accessdate = 19 August 2009}}</ref> Societates [[ViroPharma]] et [[Schering-Plough]] medicamentum antivirale, [[pleconaril]], evolvunt, quod [[Picornaviridae|picornaviridas]] petit, quae plurimas gravedines efficiunt; [[pleconaril]] iam probatum est in forma [[modus administrationis|per os administrata]] efficax (McConnell 1999; Pevear et al. 1999). [[Schering-Plough]] formulationem [[modus administrationis|per nasum administrandam]] evolvit quae fortasse pauciores effectus adversos habebit (National Institutes of Health 2007).

Investigatores [[Universitas Terrae Mariae, College Park|Universitatis Terrae Mariae, College Park]] et [[Universitas Visconsiniae–Madison|Universitatis Visconsiniae-Madison]] [[genoma]]ta omnium generum virorum quae gravedinem efficiunt tabulaverunt.<ref name="CTgov">{{cite web| url = http://www.cnn.com/2009/HEALTH/02/12/cold.genome/| title = Genetic map of cold virus a step toward cure, scientists say| month = March| year = [[2009]]| accessdate = [[28 Aprilis]] [[2009]]| publisher = [[CNN]]| work = Val Willingham}}</ref>

{{NexInt}}
* [[Influenza A virus]]
* [[Pituita]]
* [[Vitamin C et gravedo]]

== Notae ==
<references/>
 
== Bibliographia ==
{{div col}}
* Al-Nakib, W., P. G. Higgins, I. Barrow, G. Batstone, et D. A. Tyrrell. [[1987]]. "Prophylaxis and treatment of rhinovirus colds with zinc gluconate lozenges." ''Journal of Antimicrobiam Chemotherapy'' 20(6, Decembris):893–901. PMID 3440773.
* American College of Allergy, Asthma & Immunology. N.d. ''Hives.'' [http://www.acaai.org/public/advice/urtic.htm, inventum 24 Novembris 2007]{{Nexus deficitur|date=October 2022 |bot=InternetArchiveBot |fix-attempted=yes }}.
* American Lung Association. [[2005]]. ''A Survival Guide for Preventing and Treating Influenza and the Common Cold.'' Augusto. [https://web.archive.org/web/20070108231912/http://www.lungusa.org/site/pp.asp?c=dvLUK9O0E&b=35873#done, inventum 11 Iunii 2007].
* American Treasures of the Library of Congress. N.d. "Benjamin Franklin: In His Own Words." ''Scientist and Inventor.'' [http://www.loc.gov/exhibits/treasures/franklin-scientist.html ''Scientist and Inventor: Benjamin Franklin: In His Own Words... (AmericanTreasures of the Library of Congress)'' apud www.loc.gov], inventum 23 Decembris 2007.<!--Perhaps a little garbled.-->
* Andrewes, C. H., J. E. Lovelock, et T. Sommerville. [[1951]]. "An experiment on the transmission of colds." ''The Lancet'' 1(1):25–27.
* Bergner, Paul. [[1997]]. "Healing Power of Echinacea and Goldenseal and Other Immune System Herbs." ''The Healing Power.''
* Boyce, John M., et Didier Pittet. [[2002]]. "Guideline for Hand Hygiene in Health-Care Settings: Guideline for Hand Hygiene in Health-Care Settings Recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force." ''Morbidity and Mortality Weekly Report'' 51(RR-16) (25 Octobris 2002), [http://www.cdc.gov/mmwr/PDF/rr/rr5116.pdf,%20,%20inventum 21 Iunii 2007].
* Canadian Lung Association. [[2006]]. ''Common Cold.'' 28 Septembris. [http://www.lung.ca/diseases-maladies/a-z/cold-rhume/index_e.php, inventum 5 Aprilis 2009]{{Nexus deficitur|date=October 2022 |bot=InternetArchiveBot |fix-attempted=yes }}.
* Canadian Pediatric Society. [[2005]]a. ''Colds in Children.'' October. [http://www.cps.ca/caringforkids/whensick/colds.htm, inventum 16 Iulii 2007]{{Nexus deficitur|date=October 2022 |bot=InternetArchiveBot |fix-attempted=yes }}.
* Canadian Pediatric Society. [[2005]]b. ''Using over-the-counter drugs to treat cold symptoms.'' March. [http://www.cps.ca/caringforkids/whensick/otc_drugs.htm, inventum 16 Iulii 2007]{{Nexus deficitur|date=October 2022 |bot=InternetArchiveBot |fix-attempted=yes }}.
* Cathcart, Robert F. [[1996]]. "Preparation of Sodium Ascorbate for IV and IM Use." Orthomed.com, inventum 21 Februarii 2007.
* Clinical Knowledge Summaries Service. [[2007]]. ''Common Cold (Topic Review).'' [http://www.cks.library.nhs.uk/common_cold/view_whole_topic_review, inventum 21 Iulii 2007]{{Nexus deficitur|date=October 2022 |bot=InternetArchiveBot |fix-attempted=yes }}.
* Cohen, S. W. J. Doyle, C. M. Alper, D. Janicki-Deverts, et R. B. Turner. [[2009]]. "Sleep Habits and Susceptibility to the Common Cold." ''Arch. Intern. Med.'' 169(1, Ianuario):62–67.
* Common Cold Centre. [[2006]]. Cardiff University. [http://www.cardiff.ac.uk/biosi/subsites/cold/commoncold.html ''Cardiff University - Common Cold Centre'' apud www.cardiff.ac.uk], inventum 6 Septembris.
* Department of Health, Government of South Australia. [[2005]]. ''Common Cold.'' [https://web.archive.org/web/20091003004230/http://www.dh.sa.gov.au/pehs/Youve-got-what/ygw-common-cold.pdf versio interretialis (pdf) apud dh.sa.gov.au], inventum 20 Iunii 2007.
* Douglas R. C.,{{dubsig}} R. B. Couch, K. M. Lindgren. [[1967]]. "Cold doesn't affect the "common cold" in study of rhinovirus infections." ''JAMA'' 199(7):29–30.
* Douglas, R. G. Jr.,{{dubsig}} K. M. Lindgren, et R. B. Couch. [[1968]]. "Exposure to cold environment and rhinovirus common cold: Failure to demonstrate effect." ''New Engl. J. Med.''
* Dowling, H. F., G. G. Jackson, I. G. Spiesman, et T. Inouye. [[1958]]. "Transmission of the common cold to volunteers under controlled conditions. III. The effect of chilling of the subjects upon susceptibility." ''American Journal of Hygiene'' 68(1):59–65.
* Eccles, R. [[2002]]. "Acute cooling of the body surface and the common cold." ''Rhinology'' 40(3):109–114.
* Eccles, R. [[2005]]. "Understanding the symptoms of the common cold and influenza." ''Lancet Infectious Diseases'' 5(11):718–725. PMID 16253889. DOI 10.1016/S1473-3099(05)70270-X.
* Fendrick, A. M., A. S. Monto, B. Nightengale, et M. Sarnes. [[2003]]. "The economic burden of non-influenza-related viral respiratory tract infection in the United States." ''Arch. Intern. Med.'' 163(4):487–494. PMID 12588210. http://archinte.ama-assn.org/cgi/content/full/163/4/487.
* Garibaldi, R. A. [[1985]]. "Epidemiology of community-acquired respiratory tract infections in adults: Incidence, etiology, and impact." ''Am. J. Med.'' 78(6B):32–37. PMID 4014285.
* Gwaltney, J. M., et F. G. Hayden. [[2006]]. "Understanding Colds." [http://www.commoncold.org/index.htm ''Common Cold'' apud www.commoncold.org], inventum 3 Iulii 2007.
* Gwaltney, J. M., et F. G. Hayden. [[2007]]. "Understanding the Common Cold: How Cold Virus Infection Occurs." [https://web.archive.org/web/20140311213957/http://www.commoncold.org/undrstn3.htm ''Understanding the Common Cold: How Cold Virus Infection Occurs'' apud www.commoncold.org].
* Hamel, Paul B., et Mary U. Chiltoskey. [[1975]]. ''Cherokee Plants and Their Uses—A 400 Year History.'' Sylva, N.C.: Herald Publishing Co.
* Hamilton, Patsy. N.d. "Facts about the Common Cold Incubation Period." [https://web.archive.org/web/20071014125019/http://healthguidance.org/entry/6125/1/Facts-about-the-Common-Cold-Incubation-Period.html ''Facts about the Common Cold Incubation Period'' apud www.healthguidance.org], inventum 3 Iulii 2007.
* Heikkinen, T., et A. Järvinen. [[2003]]. "The common cold." ''The Lancet'' 361(9351):51–59.
* Jakes, Susan. [[2007]]. ''Beverage of Champions.'' 15 Ianuarii. Inventum 2 Augusti 2007.
* Jimenez-Medina E, et al. [[2006]]. "A new extract of the plant Calendula officinalis produces a dual in vitro effect: cytotoxic anti-tumor activity and lymphocyte activation." ''BMC Cancer'' 6:6.
* Johnson, C., et R. Eccles. [[2005]]. "Acute cooling of the feet and the onset of common cold symptoms." ''Family Practice'' 22(6):608–613. [http://fampra.oxfordjournals.org/cgi/content/full/22/6/608%7D%7D%3C/ref%3E%3Cref%3E].
* Kolata, Gina. [[2007]]. "Study Shows Why the Flu Likes Winter." ''New York Times.'' 5 Decembris. [http://www.nytimes.com/2007/12/05/health/research/05flu.html ''The New York Times &gt; Log In'' apud www.nytimes.com].
* McConnell, J. [[1999]]. "Enteroviruses succumb to new drug." ''The Lancet'' 354(9185):1185, 2 Octobris.
* The Merck Manual Online. [[2005]]. ''Common Cold (Upper Respiratory Infection).'' Novembris. Merck & Co. [http://www.merck.com/mmpe/sec14/ch188/ch188c.html], inventum 13 Iunii 2007.
* National Center for Complementary and Alternative Medicine. [[2005]]. "Echinacea for the Prevention and Treatment of Colds in Adults: Research Results and Implications for Future Studies." Octobri. [http://nccam.nih.gov/research/results/echinacea_rr.htm%7D%7D%3C]{{Nexus deficitur|date=October 2022 |bot=InternetArchiveBot |fix-attempted=yes }}.
* National Institute of Allergy and Infectious Diseases. [[2006]]. ''Common Cold.'' 27 Novembris. [http://www3.niaid.nih.gov/healthscience/healthtopics/colds], inventum 11 Iunii 2007.
* National Institutes of Health. [[2007]]."Effects of Pleconaril Nasal Spray on Common Cold Symptoms and Asthma Exacerbations Following Rhinovirus Exposure (Study P04295AM2)." [http://www.clinicaltrials.gov/ct/gui/show/NCT00394914 ex ClinicalTrials.gov], inventum 10 Aprilis 2007.
* ''New England Journal of Medicine.'' [[2005]]. "An Evaluation of Echinacea angustifolia in Experimental Rhinovirus Infections. Iulio. [http://content.nejm.org/cgi/content/abstract/353/4/341%7D%7D%3C/ref%3E%3Cref%3E%7B%7B]{{Nexus deficitur|date=October 2022 |bot=InternetArchiveBot |fix-attempted=yes }}.
* Nordenberg, Tamar. [[1999]]. "Colds and Flu: Time Only Sure Cure." [[Food and Drug Administration]] (Maio 1999). [http://www.fda.gov/fdac/features/896_flu.htmlm, inventum 13 Iunii 2007].
* Online Etymology Dictionary. N.d. "Cold." [http://www.etymonline.com/index.php?term=cold ''Online Etymology Dictionary'' apud www.etymonline.com], inventum 12 Ianuarii 2008.
* PDR Health. N.d. "Common Cold." Thomson Healthcare. [https://web.archive.org/web/20090329035121/http://pdrhealth.com/disease/disease-mono.aspx?contentFileName=BHG01ID25.xml&contentName=Common+Cold&contentId=30], inventum 11 Iulii 2007.
* Pevear, Daniel C., Tina M. Tull, Martin E. Seipel, James M. Groarke. [[1999]]. "Activity of Pleconaril against Enteroviruses" ''Antimicrobial Agents and Chemotherapy'' 43(9):2109–2115.
* Public Health Agency Canada. [[2008]]. ''Staying healthy is in your hands." [https://web.archive.org/web/20100307160451/http://www.phac-aspc.gc.ca/chn-rcs/handwash-eng.php ''Staying healthy is in your hands - Public Health Agency Canada'' apud www.phac-aspc.gc.ca], inventum 5 Maii 2008.
* Schneider Reto U. [[2004]]. ''Das Buch der verrückten Experimente (Broschiert).'' ISBN 3-442-15393-X. [http://www.verrueckte-experimente.de/index_e.html%7D%7D%3C].
* Simasek, M., et D. A. Blandino. [[2007]]. "Treatment of the common cold." ''American family physician'' 75(4):515–520. PMID 17323712. [https://web.archive.org/web/20070926230125/http://www.aafp.org/afp/20070215/515.html ''Treatment of the Common Cold - February 15, 2007 - American Family Physician'' apud www.aafp.org].
* Smith, Michael. [[2005]]. "Cold Feet? Aah-Choo!" ''Medical News: Flu & URI, Medpagetoday.'' 14 Novembris. [http://www.medpagetoday.com/Pulmonary/URIstheFlu/tb/2136.http://aac.asm.org/cgi/content/full/43/9/2109 ''Medical News: Cold Feet? Aah-Choo! - in Infectious Disease, Flu & URI from MedPage Today'' apud www.medpagetoday.com].
* Turner, R. B., et al. [[2005]]. "An Evaluation of ''Echinacea angustifolia'' in Experimental Rhinovirus Infections." ''New England Journal of Medicine'' 353:341–348. 
* Tyrrell, D. A. [[1987]]. "Interferons and their clinical value." ''Rev. Infect. Dis.'' 9(2):243–249.
* Tyrrell, D. A. [[1988]]. "Hot news on the common cold." ''Annual Rev. Microbiol.'' 42:35–47.
* UpToDate Inc. N.d. [http://www.uptodate.com/online/content/topic.do?topicKey=pedi_id/16291&selectedTitle=1~116&source=search_result#20 ''UpToDate Inc.'' apud www.uptodate.com].
* Wylie, A. [[1927]]. "Rhinology and Laryngology in Literature and Folk-Lore." ''The Journal of Laryngology & Otology'' 42(2):81–87.
* Zuger, Abigail. [[2003]]. "'You'll Catch Your Death!' An Old Wives' Tale? Well. . . ." ''[[The New York Times]]'' 4 Martii. [http://query.nytimes.com/gst/fullpage.html?res=9D02E1DD163FF937A35750C0A9659C8B63 '''You'll Catch Your Death!' An Old Wives' Tale? Well . . . - The New York Times'' apud query.nytimes.com], inventum 817 17 Decembris.
{{div col end}}

{{1000 paginae}}

[[Categoria:Inflammationes|Nasopharyngitis]]
[[Categoria:Morbi a concubitu sexuum transmissi]]
[[Categoria:Morbi virales]]
[[Categoria:Vira]]

{{Myrias|Biologia}}