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Fasciculus:Serpin equilibrium.png

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E Vicipaedia

Sua resolutio(3 000 × 1 902 elementa imaginalia, magnitudo fasciculi: 1.41 megaocteti, typus MIME: image/png)

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Summarium

Descriptio
English: The native state of serpins is an equilibrium between a fully-stressed state (left) and a partially relaxed state (right). The five-stranded A-sheet (light blue) contains two functionally important regions for the serpin's mechanism, the breach and the shutter. The Reactive Centre Loop (RCL, blue) exists in a dynamic equilibrium between the fully exposed conformation (left) and a conformation where it is partially inserted into the breach of the A-sheet (right). (PDB: 1QLP, 1YXA​). [1] [2]
Datum
Fons Opus proprium
Auctor Thomas Shafee

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This file is licensed under the Creative Commons Attribution 4.0 International license.
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  1. Elliott PR, Lomas DA, Carrell RW, Abrahams JP. (1996). "Inhibitory conformation of the reactive loop of alpha 1-antitrypsin". Nature Structural & Molecular Biology 3 (8): 676–81. DOI:10.1038/nsb0896-676. PMID 8756325.
  2. (2005). "The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins.". J Biol Chem 280 (52): 43168–78. DOI:10.1074/jbc.M505598200. PMID 16141197.

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depicts Anglica

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14 Decembris 2015

media type Anglica

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Historia fasciculi

Presso die vel tempore fasciculum videbis, sicut tunc temporis apparuit.

Dies/TempusMinutioDimensionesUsorSententia
recentissima23:23, 6 Octobris 2016Minutum speculum redactionis 23:23, 6 Octobris 2016 factae3 000 × 1 902 (1.41 megaocteti)CmdrjamesonCompressed with pngout. Reduced by 772kB (34% decrease).
23:05, 19 Martii 2016Minutum speculum redactionis 23:05, 19 Martii 2016 factae3 000 × 1 902 (2.16 megaocteti)Evolution and evolvabilityColour tweaks
12:05, 14 Decembris 2015Minutum speculum redactionis 12:05, 14 Decembris 2015 factae1 246 × 765 (476 chiliocteti)Evolution and evolvabilityCross-wiki upload from en.wikipedia.org

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