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Fasciculus:PegUricase.png

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E Vicipaedia

Sua resolutio(2 192 × 2 136 elementa imaginalia, magnitudo fasciculi: 1.65 megaocteti, typus MIME: image/png)

Hic fasciculus apud Vicimedia Communia iacet; in aliis inceptis adhiberi potest. Contenta paginae descriptionis fasciculi subter monstrantur.

Summarium

Descriptio
English: A comparison of uricase (pdb:1uox) and PEG-uricase (model). PEG-uricase includes 40 polymers of 10kDa PEG. PEGylation improves its solubility at physiological pH, increases serum half-life and reduces immunogenicity without compromising activity. Upper images show the whole tetramer, lower images show an example of one of the lysines that is PEGylated. (PEG-uricase model from reference[1], only 36 PEG polymers included)
Datum
Fons Opus proprium
Auctor Evolution and evolvability

Potestas usoris

I, the copyright holder of this work, hereby publish it under the following license:
w:en:Creative Commons
attributio
This file is licensed under the Creative Commons Attribution 4.0 International license.
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  • communicare – copiare, distribuere et committere hoc opus
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  1. (3 January 2008). "PEG-uricase in the management of treatment-resistant gout and hyperuricemia.". Advanced drug delivery reviews 60 (1): 59-68. PMID 17826865.

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depicts Anglica

PEGylation Anglica

pegloticase Anglica

uricase Anglica

copyrighted Anglica

22 Februarii 2015

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Presso die vel tempore fasciculum videbis, sicut tunc temporis apparuit.

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recentissima23:50, 21 Februarii 2015Minutum speculum redactionis 23:50, 21 Februarii 2015 factae2 192 × 2 136 (1.65 megaocteti)Evolution and evolvabilityUser created page with UploadWizard

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