Fasciculus:DE landscape.png
Mensura huius perspectionis: 800 × 470 elementa imaginalia. Aliae mensurae: 320 × 188 elementa imaginalia | 640 × 376 elementa imaginalia | 957 × 562 elementa imaginalia.
Sua resolutio (957 × 562 elementa imaginalia, magnitudo fasciculi: 327 chiliocteti, typus MIME: image/png)
Summarium
| Descriptio |
English: Performing multiple rounds of directed evolution is useful not only because a new library of mutants is created in each round but also because each new library uses better mutants as templates. The experiment is analogous to climbing a hill on a 'fitness landscape' where elevation represents the desired property. The goal is to reach the summit, which represents the best achievable mutant. Each round of selection samples mutants on all sides of the starting template (1) and selects the mutant with the highest elevation, thereby climbing the hill. This is repeated until a local summit is reached (2). |
| Datum | |
| Fons | Thomas, Shafee, (2014). "Evolvability of a viral protease: experimental evolution of catalysis, robustness and specificity". PhD Thesis. University of Cambridge. |
| Auctor | Thomas Shafee |
Potestas usoris
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Historia fasciculi
Presso die vel tempore fasciculum videbis, sicut tunc temporis apparuit.
| Dies/Tempus | Minutio | Dimensiones | Usor | Sententia | |
|---|---|---|---|---|---|
| recentissima | 00:29, 14 Decembris 2014 | | 957 × 562 (327 chiliocteti) | Evolution and evolvability | increased axis title size |
| 00:15, 14 Decembris 2014 |  | 957 × 562 (282 chiliocteti) | Evolution and evolvability | User created page with UploadWizard |
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