Vitaminum B12

Vitaminum B₁₂ alias cobalaminum est biomolecula in aqua solubilis et atomum cobalti amplexa quae cofactor plurium enzymorum in animalibus invenitur. Erythrocytorum maturationi et aliis viis metabolicis ad nucleica acida pertinentibus inprimis necessaria est (eius absentia letalis est). Sed ex hominis intestino in ileo non exhauritur nisi prius a factore "intrinsecus" dicto ligatum est quem cellulae parietales in stomachi cavum excernunt. Cobalaminum in carne, pisce, ovis, lacte sufficienter^[1] versatur: qui defectu huius vitamini laborant sunt igitur in primis senes et vegani et ii quibus stomachus ablatus est ita ut cobalaminum intra musculos eis iniciatur^[2].

Cobalamini defectus anaemiam perniciosam^[3] gignit et multas systematis nervosi perturbationes: torporem, mentis confusionem, corporis libramentum labefactum et labantem memoriam.

Ruminantium saluti quoque utile est cobaltum adeo ut nonnumquam eorum cibo addatur^[4] quia bacteria in eorum stomachis fervore vitaminum B₁₂ naturaliter fabricantur.

Notae

↑ la nutrition.fr
↑ Omar Ahmed Abdelwahab, Ahmed Abdelaziz, Sherein Diab, Ali khazragy, Toka Elboraay, Taha Fayad, Rehab Adel Diab & Ahmed Negida. "Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis", Irish Journal of Medical Science, 2024: 1621–1639, (2024)
↑ passeportsanté. Pernicious anaemia society.
↑ R. Wolter. "Besoins vitaminiques des ruminants". Productions Animales, 1988: 311-318. González-Montaña JR, et alii. "Relationship between Vitamin B12 and Cobalt Metabolism in Domestic Ruminant: An Update". Animals (Basel), 2020:1855. Chiara Marchese, et alii. "Cobalt in feed: A first survey in Italy", Journal of Trace Elements in Medicine and Biology 2025: 127637.

Plura legere si cupis

Nikita A. Kuldyushev, Sergey Y. Simonenko, Semen I. Goreninskii, Tatiana N. Pallaeva, Andrey A. Zamyatnin, Jr. etAlessandro Parodi. "From Nutrient to Nanocarrier: The Multifaceted Role of Vitamin B12 in Drug Delivery", International Journal of Molecular Sciences, 2025: 1119.
Stefan Markun, Isaac Gravestock, Levy Jäger, Thomas Rosemann, Giuseppe Pichierri, Jakob M Burgstaller. "Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression", Nutrients, 2021:923.
Patryk Mucha, Filip Kus, Dominik Cysewski, Ryszard T. Smolenski et Marta Tomczyk. "Vitamin B12 Metabolism: A Network of Multi-Protein Mediated Processes", International Journal of Molecular Sciences, 2024: 8021
Deepanshi Sharma, Amandeep Singh, Yash Prashar. "Vitamin B12: A cornerstone of cognitive and metabolic well-being in young adults", Obesity Medicine, 2025: 100563
Žane Temova Rakuša, Robert Roškar, Neal Hickey, Silvano Geremia. "Vitamin B12 in Foods, Food Supplements, and Medicines—A Review of Its Role and Properties with a Focus on Its Stability", Molecules, 2022: 240

Nexus externi

Vicimedia communia plura habent quae ad vitaminum B12 pertinent.
Librorum capitula de vitamino B12 nuper publicata apud ScienceDirect

[1] utrition.fr

[2] Omar Ahmed Abdelwahab, Ahmed Abdelaziz, Sherein Diab, Ali khazragy, Toka Elboraay, Taha Fayad, Rehab Adel Diab & Ahmed Negida. "Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis", Irish Journal of Medical Science, 2024: 1621–1639, (2024)

[3] sseportsanté. Pernicious anaemia society.

[4] R. Wolter. "Besoins vitaminiques des ruminants". Productions Animales, 1988: 311-318. González-Montaña JR, et alii. "Relationship between Vitamin B12 and Cobalt Metabolism in Domestic Ruminant: An Update". Animals (Basel), 2020:1855. Chiara Marchese, et alii. "Cobalt in feed: A first survey in Italy", Journal of Trace Elements in Medicine and Biology 2025: 127637.

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