Receptorium glucocorticoidorum
Receptoria glucocorticoidorum (RG) sunt receptoria quibus glucocorticoida ut cortisolum ligant, ita effectus provocantia[1]. Distinguuntur receptorium glucocorticoidorum nucleare (RGn, iter "classicum") et receptorium glucocorticoidorum membranaceum (RGm, iter "non classicum")[2][3].
RG nuclearia transscriptio (biologia) genorum gubernant. Reperiuntur receptoria haec pleraque in cellulis. De consuetudine in cytoplasmate invenitur, at cum glucocorticoido ligato in nucleo movetur.
RG membranacea extra cortisolum aliena glucorticoida exogena, ut dexamethasonum, ligant. Munus eorum est responsum rapidum contentione causa transmittendi.
Notae[recensere | fontem recensere]
- ↑ Heitzer M. D., Wolf I. M., Sanchez E. R., Witchel S. F., DeFranco D. B. (Dec 2007). "Glucocorticoid receptor physiology". Reviews in endocrine & metabolic disease 8 (4): 321-30
- ↑ Revollo J. R., Cidlowski J. A. (Oct 2009). "Mechanisms generating diversity in glucocorticoid receptor signaling". Annals of the New York Academy of Sciences 1179: 167-78
- ↑ Samarasinghe R. A., Witchell S. F., DeFranco D. B. (Aug 2012). "Cooperativity and complementarity: synergies in non-classical and classical glucocorticoid signaling". Cell Cycle 11 (15): 2819-27
Nexus interni
Nexus externi[recensere | fontem recensere]
- wikipathwaysde receptoriis glucocorticoidorum (Anglice)