Porphobilinogeni deaminasis
| Porphobilinogeni deaminasis HMB S | |||||
|---|---|---|---|---|---|
| Cognitores | |||||
| Alia nomina | HMBS | ||||
| Numerus EC | 2.5.1.61 (transferasis) | ||||
| Fontes externae | OMIM: 609806 | ||||
| Genetica | |||||
| Locus geni (homo) | |||||
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 | |||||
| Locus | 11q23.3 | ||||
| Initium | 119 084 866 | ||||
| Terminus | 119 093 549 | ||||
| Biochemia | |||||
| Substratum | Porphobilinogenum | ||||
Porphobilinogeni deaminasis (numerus EC: 2.5.1.61) est enzymum, quod porphobilinogenum in hydroxymethylobilanum convertit.
Enzymum praecipue in cytoplasmate exprimitur.
Mutationes geni enzymi morbum porphyriae intermittentis acutae efficit[1].
Genetica
[recensere | fontem recensere]Genum enzymi porphobilinogeni deaminasis, HMBS2 nominatum, in hominibus in chromosomate 11 invenitur.
Nexus interni
Notae
[recensere | fontem recensere]- ↑ Gill R., Kolstoe S. E., et al. (Apr 2009). "Structure of human porphobilinogen deaminase at 2.8 A: the molecular basis of acute intermittent porphyria". The biochemical journal 420 (1): 17-25
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