Phenylpiperazinum

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Phenylpiperazini structura chemica.

Phenylpiperazinum est compositum chemicum organicum cum grege chemico phenyli et anulo piperazini. Nonumquam medicamentorum suffixum -piprazolum substantiam phenylpiperazinum continere indicat, ut Aripiprazolum.

Phenylpiperazina in multis medicamentis inveniuntur. Nuper grex inhibitorum IGF-1R descriptus est[1]. Proteinum IGF-1 cancerogenesis momentum habere videtur[2].

Nexus interni

Notae[recensere | fontem recensere]

  1. Guo FJ, Sun J, Gao LL1, Wang XY, Zhang Y1, Qian SS1, Zhu HL (2015). "Discovery of phenylpiperazine derivatives as IGF-1R inhibitor with potent antiproliferative properties in vitro". Bioorg Med Chem Lett 25 (5): 1067-71 
  2. Yang y, Yee D (2012). "Targeting insulin and insulin-like growth factor signaling in breast cancer". J Mammary Gland Biol Neoplasia 17 (3-4): 251-61 

Nexus externi[recensere | fontem recensere]

  • Pubchem de phenylpiperazino. (Anglice)