Folliculos stimulans hormon

Folliculos stimulans hormon, abbreviatura FSH, est hormon ex duabus catenis, alpha (FSHA, OMIM: 118850) et beta (FSHB, OMIM: 136530), compositum. FSH de cellula gonadotropica lobi anterioris hypophysis secernitur. Et in viribus et in muliebris hormono FSH munera propria sunt.

Physiologia FSH[recensere | fontem recensere]

Secretio[recensere | fontem recensere]

Secretio hormontis folliculos stimulantis praecipue ab hypothalamo per decapeptidum hormon liberationis gonadotropinorum (GnRH) moderatur; secretio ipsa ab cellulas gonadotropicas, quae in lobo anteriori hypophysis sitae sunt, fit^[1]. Intra hypophysi, complexus proteinorum et activini (biosynthesis FSH ↑) et inhibini (biosynthesis FSH ↓), velut follistatinum in edita moderandis agunt^[2]. Activinum genum promotorem Fshb subunitatis beta lectum incitat. Subunitas alpha, ut LH, genum alphaGSU requirit.

Cyclus mensualis apud muliebres[recensere | fontem recensere]

Cyclo menstruali ineunte FSH folliculos in ovariis immaturos stimulat^[3].

Spermatogenesis apud viros[recensere | fontem recensere]

FSH spermatocytos in testibus virorum stimulat^[4].

Notae[recensere | fontem recensere]

↑ Sharma T. P., Nett T. M., Karsch F. J., Phillips D. J., Lee J. S., Herkimer C., Padmanabhan V. (2012). "Neuroendocrine control of FSH secretion: IV. Hypothalamic control of pituitary FSH-regulatory proteins and their relationship to changes in FSH synthesis and secretion". Biology of reproduction 86 (6): 171 doi:10.1095/biolreprod.111.098442
↑ Bilezikjian L. M., Justice N. J., Blackler A. N., Wiater E., Vale W. W. (Aug 2021). "Cell-type specific modulation of pituitary cells by activin, inhibin and follistatin". Molecular and cellular endocrinology 359 (1-2): 43-52 doi:10.1016/j.mce.2012.01.025
↑ Messinis I. E., Messini C. I., Dafopoulos K. (2014). "Novel aspects of the endocrinology of the menstrual cycle". Reproductive biomedicine online 28 (6): 714-22
↑ Huhtaniemi I. (2015). "A short evolutionary history of FSH-stimulated spermatogenesis". Hormones (Athens, Greece) 14 (4): 468-78

Nexus interni

Nexus externi[recensere | fontem recensere]

Laboratorium et FSH. (Anglice)

Haec stipula ad biologiam spectat. Amplifica, si potes!

[1] Sharma T. P., Nett T. M., Karsch F. J., Phillips D. J., Lee J. S., Herkimer C., Padmanabhan V. (2012). "Neuroendocrine control of FSH secretion: IV. Hypothalamic control of pituitary FSH-regulatory proteins and their relationship to changes in FSH synthesis and secretion". Biology of reproduction 86 (6): 171 doi:10.1095/biolreprod.111.098442

[2] Bilezikjian L. M., Justice N. J., Blackler A. N., Wiater E., Vale W. W. (Aug 2021). "Cell-type specific modulation of pituitary cells by activin, inhibin and follistatin". Molecular and cellular endocrinology 359 (1-2): 43-52 doi:10.1016/j.mce.2012.01.025

[3] Messinis I. E., Messini C. I., Dafopoulos K. (2014). "Novel aspects of the endocrinology of the menstrual cycle". Reproductive biomedicine online 28 (6): 714-22

[4] Huhtaniemi I. (2015). "A short evolutionary history of FSH-stimulated spermatogenesis". Hormones (Athens, Greece) 14 (4): 468-78

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