Anandamidum

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Anandamidum
Cognitores
ChemSpider 4445241
PubChem 5281969
Natura chemica
Anandamidum
Anandamidum
Formula summarum C
22
H
37
NO
2
Massa molaris 347.53 g/mol

Anandamidum vel N-arachidonoylaethanolaminum (AEA) est neurotransmissor et unctoacidum ab acido arachidonico, uno unctoacidorum omega-6 essentialium, derivatum. Pars nominis prima de Lingua Sanscrita (ananda = felicitas) Lingua Sanscrita.

Effectus anandamidi cum praesentia receptoriorum cannabinoideorum nexi sunt. Putatur quoque anandamido effectus in morbis mentis esse[1].

Natura chemica[recensere | fontem recensere]

Compositum est anandamidum longa ex molecula acidi arachidonici per amino secundario cum aaethanolo (aeathanolamino) coniunctum. Nomen IUPAC est (5Z,8Z,11Z,14Z)-N-(2-hydroxy-aethyl)-icosa-5,8,11,14-tetraenamidum.

Biochemia[recensere | fontem recensere]

In hominibus synthesis anandamidi acidum arachidonicum requirit, ex quoN-arachidonoyl phosphatidylethanolaminum (NAPE) generatur.

Notae[recensere | fontem recensere]

  1. Gaetani S., Dipasquale P., Romano A., Righetti L., Cassano T., Piomelli D., Cuomo V. (2009). "The endocannabinoid system as a target for novel anxiolytic and antidepressant drugs". International review of neurobiology 85: 57-72 

Bibliographia[recensere | fontem recensere]

  • Mechoulam R., Fride E.: The unpaved road to the endogenous brain cannabinoid ligands, the anandamides in “Cannabinoid Receptors” (ed. R. Pertwee), Academic Press, London. Pp. 233-258 (1995).

Nexus interni